Fast-release oxycodone is utilized to deal with moderate to severe agony, which include from surgical procedure or an damage. OxyContin is generally reserved for for a longer period-lasting agony with the late stages of a long-expression illness, ordinarily cancer.
Retail store at home temperature far from light and humidity. Will not retail store in the toilet. Retain all prescription drugs far from youngsters and Animals. See also Warning portion.
OxyContin ought to only be used by people who have by now experimented with and tolerated shorter-acting kinds of oxycodone and which have intense discomfort necessitating round-the-clock suffering reduction. OxyContin shouldn't be taken on an 'as desired' or 'as needed' foundation.
Within the pediatric age team of 11 decades of age and more mature, systemic exposure of oxycodone is anticipated to get comparable to adults at any presented dose of OXYCONTIN.
Notify people that utilization of opioids for an prolonged time frame may perhaps result in reduced fertility. It's not at all known irrespective of whether these results on fertility are reversible [see Use In Particular Populations].
Noroxycodone displays quite weak anti-nociceptive potency as compared to oxycodone, however, it undergoes additional oxidation to create noroxymorphone, which is active at opioid receptors. Though noroxymorphone can be an active metabolite and existing at somewhat superior concentrations in circulation, here it doesn't look to cross the blood-Mind barrier to a significant extent. Oxymorphone is existing while in the plasma only at very low concentrations and undergoes even more metabolism to form its glucuronide and noroxymorphone.
Never transform your dose. Take OXYCONTIN just as prescribed by your Health care supplier. Use the bottom dose doable to the shortest time needed.
The conversion components With this desk are only for the conversion from one of many mentioned oral opioid analgesics to OXYCONTIN.
Discuss with your healthcare provider Should the pain that you've got will increase, if you are feeling a lot more delicate to discomfort, or When you've got new ache just after having OXYCONTIN.
Never abruptly discontinue OXYCONTIN within a affected person bodily depending on opioids. When discontinuing OXYCONTIN in a very bodily dependent individual, little by little taper the dosage.
The tablet strengths describe the quantity of oxycodone for every pill since the hydrochloride salt. The structural formula for oxycodone hydrochloride is as follows:
When critical, lifestyle-threatening, or get more info deadly respiratory melancholy can manifest Anytime for the more info duration of using OXYCONTIN, the chance is biggest in the initiation of therapy or following a dosage boost.
Examine The provision of naloxone with the crisis cure of opioid overdose Together with the individual and caregiver and assess the potential require for use of naloxone, both when initiating and renewing procedure with OXYCONTIN. Notify patients and caregivers about the assorted approaches to get naloxone as permitted by individual state naloxone dispensing and prescribing demands or pointers (e.
Make contact with area condition Qualified licensing board or state-controlled substances authority for info on how to stop and detect abuse or diversion of the product or service.